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Gastric cancer in Lynch syndrome is associated with underlying immune gastritis

4 May 2019

Abstract excerpt

Lynch syndrome is the most common cause of hereditary colon cancer but is also associated with gastric cancer.1 Interestingly, gastric cancer was a distinguishing feature of the original Lynch pedigree described in 1913.2 Currently, the standardised incidence ratio (SIR) for gastric cancer in Lynch syndrome is estimated to be 3.4.3 Among 255 gene-positive patients with Lynch followed prospectively in our...

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PMID: 31055502
DOI: 10.1136/jmedgenet-2018-105757

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