Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice

Abstract excerpt

Nanophthalmos is a rare, potentially devastating eye condition characterized by small eyes with relatively normal anatomy, a high hyperopic refractive error, and frequent association with angle closure glaucoma and vision loss. The condition constitutes the extreme of hyperopia or farsightedness, a common refractive error that is associated with strabismus and amblyopia in children. NNO1 was the first mapped...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ocular Diseases and Behçet’s Syndrome
• Share to Ocular Disorders and Treatments
• Share to Retinal Development and Disorders