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Article

Chemotherapy-induced oral mucositis is associated with detrimental bacterial dysbiosis

24 Apr 2019

Abstract excerpt

BACKGROUND: Gastrointestinal mucosal injury (mucositis), commonly affecting the oral cavity, is a clinically significant yet incompletely understood complication of cancer chemotherapy. Although antineoplastic cytotoxicity constitutes the primary injury trigger, the interaction of oral microbial commensals with mucosal tissues could modify the response. It is not clear, however, whether chemotherapy and its...

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PMID: 31018870
DOI: 10.1186/s40168-019-0679-5

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