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Seven-senescence-associated gene signature predicts overall survival for Asian patients with hepatocellular carcinoma

12 Apr 2019

Abstract excerpt

BACKGROUND: Cellular senescence is a recognized barrier for progression of chronic liver diseases to hepatocellular carcinoma (HCC). The expression of a cluster of genes is altered in response to environmental factors during senescence. However, it is questionable whether these genes could serve as biomarkers for HCC patients. AIM: To develop a signature of senescence-associated genes (SAGs) that predicts...

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PMID: 31011256
DOI: 10.3748/wjg.v25.i14.1715

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