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The role of caveolin-1 in tumors of the brain - functional and clinical implications

16 Apr 2019

Abstract excerpt

BACKGROUND: Caveolin-1 (cav-1) is the major structural protein of caveolae, the flask-shaped invaginations of the plasma membrane mainly involved in cell signaling. Today, cav-1 is believed to play a role in a variety of disease processes including cancer, owing to the variations of its expression in association with tumor progression, invasive behavior, metastasis and therapy resistance. Since first detected in...

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PMID: 30993541
DOI: 10.1007/s13402-019-00447-x

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