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Uromodulin-related autosomal-dominant tubulointerstitial kidney disease—pathogenetic insights based on a case

5 Sept 2018

Abstract excerpt

Uromodulin-related autosomal-dominant tubulointerstitial kidney disease (ADTKD-UMOD) is a rare monogenic disorder that is characterized by tubulointerstitial fibrosis and progression of kidney function loss, and may progress to end-stage renal disease. It is usually accompanied by hyperuricaemia and gout. Mutations in the uromodulin gene (UMOD) resulting in malfunctioning of UMOD are known to be the cause of...

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Share to Gout, Hyperuricemia, Uric Acid
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PMID: 30976393
DOI: 10.1093/ckj/sfy094

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