Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Model validity for preclinical studies in precision medicine: precisely how precise do we need to be?

5 Apr 2019

Abstract excerpt

The promise of personalized medicine is that each patient's treatment can be optimally tailored to their disease. In turn, their disease, as well as their response to the treatment, is determined by their genetic makeup and the "environment," which relates to their general health, medical history, personal habits, and surroundings. Developing such optimized treatment strategies is an admirable goal and success...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Genomics and Rare Diseases
Share to Neurogenetic and Muscular Disorders Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30953144
DOI: 10.1007/s00335-019-09798-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Model validity for preclinical studies in precision medicine: precisely how precise do we need to be?PMID 30953144Read ↗

Foundations, promises and uncertainties of personalized medicine.Semantic proximity Read ↗

Development of Targeted Therapies Based on Gene Modification.Semantic proximity Read ↗

Therapeutic promise of molecular genetics.Semantic proximity Read ↗

Personalized medicine: progress and promise.Semantic proximity Read ↗

Systems diagnostics: anticipating the next generation of diagnostic tests based on mechanistic insight into disease.Semantic proximity Read ↗

Modeling human disease phenotype in model organisms: "It's only a model!".Semantic proximity Read ↗

The genetics of health.Semantic proximity Read ↗

Refining the impact of genetic evidence on clinical successSemantic proximity Read ↗

Personalized, Precision, and N-of-One Medicine: A Clarification of Terminology and Concepts.Semantic proximity Read ↗

Mechanistic systems modeling to guide drug discovery and development.Semantic proximity Read ↗

Personalized medicine: the future of Modern MedicineSemantic proximity Read ↗

Emerging Role of Precision Medicine in Cardiovascular Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.