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Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro

4 Apr 2019

Abstract excerpt

Porcine circovirus 2 (PCV2) is the main pathogen of porcine circovirus diseases and porcine circovirus-associated diseases, which are widespread in swine-producing countries. However, there is controversy regarding the susceptibility of human cells to PCV2 infection. In this study, human cell lines were infected with PCV2 and blind passaged several times. PCV2 entered and replicated in human cells, and infectious...

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PMID: 30948762
DOI: 10.1038/s41598-019-42210-0

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