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Article

Transcriptome Analyses Identify a Metabolic Gene Signature Indicative of Dedifferentiation of Papillary Thyroid Cancer

3 Apr 2019

Abstract excerpt

CONTEXT: Metabolic reprogramming is a common feature of tumorigenesis. It remains unknown concerning the expression pattern of metabolism-associated genes in dedifferentiated thyroid cancer (DDTC). OBJECTIVE: This study aimed to identify a useful signature to indicate dedifferentiation of papillary thyroid cancer (PTC). DESIGN AND SETTING: We used one discovery and two validation cohorts to screen out aberrant...

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PMID: 30942873
DOI: 10.1210/jc.2018-02686

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