Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes Mellitus

20 Mar 2019

Abstract excerpt

Gestational diabetes mellitus (GDM) is a common metabolic disorder, defined by high blood glucose levels during pregnancy, which affects foetal and post-natal development. However, the cellular and molecular mechanisms of this detrimental condition are still poorly understood. A dysregulation in circulating angiogenic trophic factors, due to a dysfunction of the feto-placental unit, has been proposed to underlie...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Apelin-related biomedical research
Share to Axon Guidance and Neuronal Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30897795
DOI: 10.3390/ijms20061408

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes MellitusPMID 30897795Read ↗

The angiogenic properties of human amniotic membrane stem cells are enhanced in gestational diabetes and associate with fetal adipositySemantic proximity Read ↗

The Role of Maternal Gestational Diabetes in Inducing Fetal Endothelial DysfunctionSemantic proximity Read ↗

Dysregulation of gene expression in human fetal endothelial cells from gestational diabetes in response to TGF-β1.Semantic proximity Read ↗

Characterization and Expression of Netrin-1 and Its Receptors UNC5B and DCC in Human PlacentaSemantic proximity Read ↗

Netrin-1: An emerging player in inflammatory diseasesSemantic proximity Read ↗

Human Milk Oligosaccharides in Cord Blood Are Altered in Gestational Diabetes and Stimulate Feto-Placental Angiogenesis In VitroSemantic proximity Read ↗

The netrin receptor UNC5B promotes angiogenesis in specific vascular beds.Semantic proximity Read ↗

BMP5 promotes trophoblast functions upon N-glycosylation via the BMP5-SMAD1/5 signaling pathway in preeclampsiaSemantic proximity Read ↗

Placental growth factor mediates pathological uterine angiogenesis by activating the NFAT5-SGK1 signaling axis in the endometrium: implications for preeclampsia developmentSemantic proximity Read ↗

miR-17-5p Promotes Glucose Uptake of HTR8/SVneo Trophoblast Cells by Inhibiting TXNIP/NLRP3 Inflammasome PathwaySemantic proximity Read ↗

The Role of Osteocalcin in Placenta Function in Gestational Diabetes MellitusSemantic proximity Read ↗

SUCNR1 is Expressed in Human Placenta and Mediates Angiogenesis: Significance in Gestational DiabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.