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A cytochrome P450 allele confers pyrethroid resistance on a major African malaria vector, reducing insecticide-treated bednet efficacy

20 Mar 2019

Abstract excerpt

allowed us to design a DNA-based assay for cytochrome P450-mediated resistance to pyrethroid insecticides. Using this assay, we tracked the spread of pyrethroid resistance and found that it was almost fixed in mosquitoes from southern Africa but was absent from mosquitoes collected elsewhere in Africa. Furthermore, a field study in experimental huts in Cameroon demonstrated that mosquitoes carrying the resistance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30894503
DOI: 10.1126/scitranslmed.aat7386

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