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Article

Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids

7 Mar 2019

Abstract excerpt

BACKGROUND: Vertebrate genomes contain a record of retroviruses that invaded the germlines of ancestral hosts and are passed to offspring as endogenous retroviruses (ERVs). ERVs can impact host function since they contain the necessary sequences for expression within the host. Dogs are an important system for the study of disease and evolution, yet no substantiated reports of infectious retroviruses in dogs...

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PMID: 30845962
DOI: 10.1186/s12977-019-0468-z

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