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MEG3 promotes liver cancer by activating PI3K/AKT pathway through regulating AP1G1.

1 Feb 2019

Abstract excerpt

OBJECTIVE: This study aims to explore the biological function of maternally expressed gene 3 (MEG3) in liver cancer and the potential mechanism of phosphatidylinositide 3-kinases/protein kinase B (PI3K/AKT) pathway in regulating proliferation and invasion of hepatoma cells. PATIENTS AND METHODS: Quantitative Real-time polymerase chain reaction (qRT-PCR) was applied to examine the level of MEG3 in 72 pairs of...

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PMID: 30840267
DOI: 10.26355/eurrev_201902_17103

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