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Article

High naevus count and MC 1R red hair alleles contribute synergistically to increased melanoma risk

1 Mar 2019

Abstract excerpt

BACKGROUND: A high total body naevus count is the highest risk factor for melanoma; the phenotype of red hair colour, freckling and pale skin that burns easily, produced by MC1R R alleles, also predisposes to melanoma. OBJECTIVES: To determine whether the known melanoma risk factors of high naevus count and red hair or MC1R R alleles act synergistically to increase melanoma risk. METHODS: The Brisbane Naevus...

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Share to Cutaneous Melanoma Detection and Management
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PMID: 30820946
DOI: 10.1111/bjd.17833

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