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epiCaPture: A Urine DNA Methylation Test for Early Detection of Aggressive Prostate Cancer

14 Jan 2019

Abstract excerpt

PURPOSE: Liquid biopsies that noninvasively detect molecular correlates of aggressive prostate cancer (PCa) could be used to triage patients, reducing the burdens of unnecessary invasive prostate biopsy and enabling early detection of high-risk disease. DNA hypermethylation is among the earliest and most frequent aberrations in PCa. We investigated the accuracy of a six-gene DNA methylation panel (Epigenetic...

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PMID: 30801051
DOI: 10.1200/po.18.00134

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