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Identification of two new core chromosome-encoded superantigens in Streptococcus pyogenes; speQ and speR

20 Feb 2019

Abstract excerpt

Superantigens are ubiquitous within the Streptococcus pyogenes genome, which suggests that superantigen-mediated T-cell activation provides a significant selective advantage. S. pyogenes can carry a variable complement of the 11 known superantigens. We have identified two novel S. pyogenes superantigens, denoted speQ and speR, adjacent to each other in the core-chromosome of isolates belonging to eleven different...

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PMID: 30796950
DOI: 10.1016/j.jinf.2019.02.005

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