Article
Evidence for microRNA-mediated regulation in rheumatic diseases.
Annals of the rheumatic diseases - 1 Jan 2010
Luo X, Tsai L M, Shen N, Yu D
Abstract excerpt
MicroRNA (miRNA), a group of short non-coding RNA of approximately 20-22 nucleotides modulating the stability and translational efficiency of target messenger RNA, present an important new layer controlling gene expression. Hundreds to a thousand miRNA have been identified and are predicted to regulate at least one-third of protein-coding transcripts in the mammalian genome. This study reviews the recent advances...
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