Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Small RNAs in Rat Sperm Are a Predictive and Sensitive Biomarker of Exposure to the Testicular Toxicant Ethylene Glycol Monomethyl Ether

15 Feb 2019

Abstract excerpt

Testicular histology and semen parameters are considered the gold standards when determining male reproductive toxicity. Ethylene glycol monomethyl ether (EGME) is a testicular toxicant with well-described effects on histopathology and sperm parameters. To compare the predictivity and sensitivity of molecular biomarkers of testicular toxicity to the traditional endpoints, small RNAs in the sperm were analyzed by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to MicroRNA in disease regulation
Share to Molecular Biology Techniques and Applications
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30768127
DOI: 10.1093/toxsci/kfz041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Small RNAs in Rat Sperm Are a Predictive and Sensitive Biomarker of Exposure to the Testicular Toxicant Ethylene Glycol Monomethyl EtherPMID 30768127Read ↗

Sperm mRNA Transcripts Are Indicators of Sub-Chronic Low Dose Testicular Injury in the Fischer 344 RatSemantic proximity Read ↗

Highly conserved sperm function-related transcripts across three species: human, rat and mouseSemantic proximity Read ↗

Exposure to Endosulfan can result in male infertility due to testicular atrophy and reduced sperm countSemantic proximity Read ↗

Alterations in sperm RNAs persist after alcohol cessation and correlate with epididymal mitochondrial dysfunctionSemantic proximity Read ↗

Sperm mRNAs and microRNAs as candidate markers for the impact of toxicants on human spermatogenesis: an application to tobacco smokingSemantic proximity Read ↗

Perturbation of epigenetic processes by doxorubicin in the mouse testisSemantic proximity Read ↗

Heavy Chronic Intermittent Ethanol Exposure Alters Small Noncoding RNAs in Mouse Sperm and EpididymosomesSemantic proximity Read ↗

High‐quality human and rat spermatozoal RNA isolation for functional genomic studiesSemantic proximity Read ↗

Mechanisms of Male Reproductive Toxicity of Polybrominated Diphenyl EthersSemantic proximity Read ↗

Analysis of the Reversible Impact of the Chemodrug Busulfan on Mouse TestesSemantic proximity Read ↗

Impact of methoxyacetic acid on mouse Leydig cell gene expressionSemantic proximity Read ↗

A molecular and phenotypic integrative approach to identify a no-effect dose level for antiandrogen-induced testicular toxicity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.