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Article

Small Molecule Follicle-Stimulating Hormone Receptor Agonists and Antagonists

23 Jan 2019

Abstract excerpt

The follicle-stimulating hormone receptor (FSHR) has been targeted therapeutically for decades, due to its pivotal role in reproduction. To date, only purified and recombinant/biosimilar FSH have been used to target FSHR in assisted reproduction, with the exception of corifollitropin alfa; a modified gonadotropin in which the FSH beta subunit is joined to the C-terminal peptide of the human choriogonadotropin...

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Share to Hypothalamic control of reproductive hormones
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PMID: 30728807
DOI: 10.3389/fendo.2018.00757

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