Article
Neutrophils escort circulating tumour cells to enable cell cycle progression.
Nature - 1 Feb 2019
Szczerba Barbara Maria, Castro-Giner Francesc, Vetter Marcus, Krol Ilona, Gkountela Sofia, Landin Julia, Scheidmann Manuel C, Donato Cinzia, Scherrer Ramona, Singer Jochen, Beisel Christian, Kurzeder Christian, Heinzelmann-Schwarz Viola, Rochlitz Christoph, Weber Walter Paul, Beerenwinkel Niko, Aceto Nicola
Abstract excerpt
A better understanding of the features that define the interaction between cancer cells and immune cells is important for the development of new cancer therapies1. However, focus is often given to interactions that occur within the primary tumour and its microenvironment, whereas the role of immune cells during cancer dissemination in patients remains largely uncharacterized2,3. Circulating tumour cells (CTCs)...
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