Fluorescence Polarization of Methylene Blue as a Quantitative Marker of Breast Cancer at the Cellular Level

Abstract excerpt

A quantitative technique to detect cancer in single cells could transform cancer diagnosis. Current cancer diagnosis utilizes histopathology, which requires tissue acquisition, extensive processing and, in most cases, relies on the qualitative morphological analysis of tissues and cells. Molecular biomarkers are only available for a few specific tumor subtypes. We discovered that the fluorescence polarization...

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