Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of the ASPM gene is associated with aggressiveness and poor outcome in bladder cancer

26 Nov 2018

Abstract excerpt

Abnormal spindle‑like microcephaly‑associated (ASPM) protein is essential for mitotic spindle function during cell replication. The present study aimed to evaluate the hypothesis that ASPM serves a critical role in cancer invasiveness and may act as a prognostic biomarker in bladder cancer. In total, 6 independent worldwide bladder cancer microarray mRNA expression datasets (n=1,355) with clinical and follow‑up...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bladder and Urothelial Cancer Treatments
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30675249
DOI: 10.3892/ol.2018.9762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of the ASPM gene is associated with aggressiveness and poor outcome in bladder cancerPMID 30675249Read ↗

ASPM Is a Prognostic Biomarker and Correlates With Immune Infiltration in Kidney Renal Clear Cell Carcinoma and Liver Hepatocellular CarcinomaSemantic proximity Read ↗

Identification of the ASPM-miR-26b-5p network associated with the aggressive traits of HCC cellsSemantic proximity Read ↗

The differential distributions of ASPM isoforms and their roles in Wnt signaling, cell cycle progression, and pancreatic cancer prognosisSemantic proximity Read ↗

Oncogenic ASPM Is a Regulatory Hub of Developmental and Stemness Signaling in CancersSemantic proximity Read ↗

Systematic screening of protein-coding gene expression identified HMMR as a potential independent indicator of unfavorable survival in patients with papillary muscle-invasive bladder cancerSemantic proximity Read ↗

ASPM and microcephalin expression in epithelial ovarian cancer correlates with tumour grade and survivalSemantic proximity Read ↗

A comprehensive molecular characterization of the 8q22.2 region reveals the prognostic relevance of OSR2 mRNA in muscle invasive bladder cancerSemantic proximity Read ↗

Snai2‐mediated upregulation of NADSYN1 promotes bladder cancer progression by interacting with PHBSemantic proximity Read ↗

Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder CancerSemantic proximity Read ↗

ASPM and TROAP gene expression as potential malignant tumor markersSemantic proximity Read ↗

STAG2 expression is associated with adverse survival outcomes and regulates cell phenotype in muscle-invasive bladder cancer.Semantic proximity Read ↗

Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent copy number variation in IPO11 and prognostic significance of importin-11 overexpression on poor survival.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.