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Article

Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia

14 Jan 2019

Abstract excerpt

BACKGROUND: Long non-coding RNAs (lncRNAs) have emerged as a novel class of RNA due to its diverse mechanism in cancer development and progression. However, the role and expression pattern of lncRNAs in molecular subtypes of B cell acute lymphoblastic leukemia (BCP-ALL) have not yet been investigated. Here, we assess to what extent lncRNA expression and DNA methylation is driving the progression of relapsed...

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PMID: 30642353
DOI: 10.1186/s13045-018-0692-3

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