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The radiobiological effects of He, C and Ne ions as a function of LET on various glioblastoma cell lines

31 Oct 2018

Abstract excerpt

The effects of the charged ion species 4He, 12C and 20Ne on glioblastoma multiforme (GBM) T98G, U87 and LN18 cell lines were compared with the effects of 200 kVp X-rays (1.7 keV/μm). These cell lines have different genetic profiles. Individual GBM relative biological effectiveness (RBE) was estimated in two ways: the RBE10 at 10% survival fraction and the RBE2Gy after 2 Gy doses. The linear quadratic model...

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PMID: 30624699
DOI: 10.1093/jrr/rry099

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