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Article

Gamma/Delta T Cells and Their Role in Protection Against Malaria

20 Dec 2018

Abstract excerpt

Whether and how gdT cells play a protective role in immunity against Plasmodium infection remain open questions. gdT cells expand in patients and mice infected with Plasmodium spp, and cytokine production and cytotoxic responses against blood-stage parasites are observed in vitro. Their expansion is associated with protective immunity induced by irradiated sporozoite immunisation, and depletion of gdT cells in...

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PMID: 30619330
DOI: 10.3389/fimmu.2018.02973

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