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Article

The DNA walk and its demonstration of deterministic chaos-relevance to genomic alterations in lung cancer.

Bioinformatics (Oxford, England) - 15 Aug 2019

Hewelt Blake, Li Haiqing, Jolly Mohit Kumar, Kulkarni Prakash, Mambetsariev Isa, Salgia Ravi

Abstract excerpt

MOTIVATION: Advancements in cancer genetics have facilitated the development of therapies with actionable mutations. Although mutated genes have been studied extensively, their chaotic behavior has not been appreciated. Thus, in contrast to naïve DNA, mutated DNA sequences can display characteristics of unpredictability and sensitivity to the initial conditions that may be dictated by the environment, expression...

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Source

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Identifiers

PMID: 30615123
DOI: 10.1093/bioinformatics/bty1021
PMCID: PMC6691335

Genes

BRAF
EGFR
KRAS
MET
NTRK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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