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Article

Disease-modifying therapies alter gut microbial composition in MS

27 Oct 2018

Abstract excerpt

Objective: To determine the effects of the disease-modifying therapies, glatiramer acetate (GA) and dimethyl fumarate (DMF), on the gut microbiota in patients with MS. Methods: Participants with relapsing MS who were either treatment-naive or treated with GA or DMF were recruited. Peripheral blood mononuclear cells were immunophenotyped. Bacterial DNA was extracted from stool, and amplicons targeting the V4...

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PMID: 30568995
DOI: 10.1212/nxi.0000000000000517

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