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Protein–protein interactions in bacteria: a promising and challenging avenue towards the discovery of new antibiotics

21 Nov 2018

Abstract excerpt

Antibiotics are potent pharmacological weapons against bacterial infections; however, the growing antibiotic resistance of microorganisms is compromising the efficacy of the currently available pharmacotherapies. Even though antimicrobial resistance is not a new problem, antibiotic development has failed to match the growth of resistant pathogens and hence, it is highly critical to discover new anti-infective...

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PMID: 30546472
DOI: 10.3762/bjoc.14.267

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