Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis.

doi:10.1093/ije/dyy273

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Article

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis.

International journal of epidemiology - 1 Feb 2019

Hartwig Fernando Pires, Davies Neil Martin, Horta Bernardo Lessa, Ahluwalia Tarunveer S, Bisgaard Hans, Bønnelykke Klaus, Caspi Avshalom, Moffitt Terrie E, Poulton Richie, Sajjad Ayesha, Tiemeier Henning W, Dalmau-Bueno Albert, Guxens Mònica, Bustamante Mariona, Santa-Marina Loreto, Parker Nadine, Paus Tomáš, Pausova Zdenka, Lauritzen Lotte, Schnurr Theresia M, Michaelsen Kim F, Hansen Torben, Oddy Wendy, Pennell Craig E, Warrington Nicole M, Davey Smith George, Victora Cesar Gomes

Abstract excerpt

BACKGROUND: Accumulating evidence suggests that breastfeeding benefits children's intelligence, possibly due to long-chain polyunsaturated fatty acids (LC-PUFAs) present in breast milk. Under a nutritional adequacy hypothesis, an interaction between breastfeeding and genetic variants associated with endogenous LC-PUFAs synthesis might be expected. However, the literature on this topic is controversial. METHODS:...

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PMID: 30541029
DOI: 10.1093/ije/dyy273
PMCID: PMC6380307

Genes

FADS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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