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Comparative Transcriptomics in Ebola Makona-Infected Ferrets, Nonhuman Primates, and Humans

19 Jul 2018

Abstract excerpt

The domestic ferret is a uniformly lethal model of infection for 3 species of Ebolavirus known to be pathogenic in humans. Reagents to systematically analyze the ferret host response to infection are lacking; however, the recent publication of a draft ferret genome has opened the potential for transcriptional analysis of ferret models of disease. In this work, we present comparative analysis of longitudinally...

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PMID: 30476250
DOI: 10.1093/infdis/jiy455

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