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Article

Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells.

International journal of cancer - 15 Apr 2008

Deubzer Hedwig E, Ehemann Volker, Westermann Frank, Heinrich Ralf, Mechtersheimer Gunhild, Kulozik Andreas E, Schwab Manfred, Witt Olaf

Abstract excerpt

The survival rate of children with advanced neuroblastoma (NB) is dismal despite intensive multimodal therapy. The limited efficacy and the frequent and serious side effects of currently used therapeutic regimens necessitate the development of new, less toxic treatment strategies. This study show...

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Source

Identifiers

PMID: 18074352
DOI: 10.1002/ijc.23295

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18074352-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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