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Article

Methylome profiling of healthy and central precocious puberty girls

22 Nov 2018

Abstract excerpt

BACKGROUND: Recent studies demonstrated that changes in DNA methylation (DNAm) and inactivation of two imprinted genes (MKRN3 and DLK1) alter the onset of female puberty. We aimed to investigate the association of DNAm profiling with the timing of human puberty analyzing the genome-wide DNAm patterns of peripheral blood leukocytes from ten female patients with central precocious puberty (CPP) and 33 healthy girls...

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Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Hypothalamic control of reproductive hormones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30466473
DOI: 10.1186/s13148-018-0581-1

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