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Genetic variants influence on the placenta regulatory landscape

19 Nov 2018

Abstract excerpt

From genomic association studies, quantitative trait loci analysis, and epigenomic mapping, it is evident that significant efforts are necessary to define genetic-epigenetic interactions and understand their role in disease susceptibility and progression. For this reason, an analysis of the effects of genetic variation on gene expression and DNA methylation in human placentas at high resolution and whole-genome...

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PMID: 30452450
DOI: 10.1371/journal.pgen.1007785

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