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Article

Triptolide as a novel agent in pancreatic cancer: the validation using patient derived pancreatic tumor cell line

12 Nov 2018

Abstract excerpt

BACKGROUND: Triptolide induces apoptosis and DNA damage followed by inhibition of DNA repair associated gene expression. However, there is the limited data for biomarker to predict the benefit to triptolide in various cancers including pancreatic cancer. METHODS: We investigated the anti tumor efficacy of triptolide in various pancreatic cancer cell lines (Capan-1, Capan-2, SNU-213, SNU-410, HPAFII, and Hs766T)...

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PMID: 30419860
DOI: 10.1186/s12885-018-4995-0

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