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Fragile X syndrome and connective tissue dysregulation

10 Nov 2018

Abstract excerpt

Fragile X syndrome (FXS) is the most common cause of inherited intellectual disabilities and autism spectrum disorders, and it is an X-linked disorder in which there is a deficiency of the fragile X mental retardation 1 protein. This protein is crucial in regulating translation of mRNAs related to dendritic maturation and cognitive development. The phenotype of FXS is characterized by neurobehavioral alterations,...

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PMID: 30414172
DOI: 10.1111/cge.13469

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