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Mammalian Sex Chromosome Structure, Gene Content, and Function in Male Fertility

9 Nov 2018

Abstract excerpt

Mammalian sex chromosomes evolved from an ordinary pair of autosomes. The X chromosome is highly conserved, whereas the Y chromosome varies among species in size, structure, and gene content. Unlike autosomes that contain randomly mixed collections of genes, the sex chromosomes are enriched in testis-biased genes related to sexual development and reproduction, particularly in spermatogenesis and male fertility....

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Share to Chromosomal and Genetic Variations
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PMID: 30412673
DOI: 10.1146/annurev-animal-020518-115332

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