Diseases Common in Persons With Cystic Fibrosis Among CFTR Heterozygotes.

Abstract excerpt

Importance: Cystic fibrosis is one of the most commonly diagnosed autosomal recessive disorders in the US. It is estimated that more than 10 million individuals are heterozygous for a pathogenic CFTR gene variant in the US (heterozygotes). The phenotypic risk of these heterozygotes is not well defined, particularly among populations of predominantly non-European genetic ancestry. Understanding disease risk across...

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• Cystic Fibrosis
• Cystic Fibrosis Research Advances
• Cystic Fibrosis Transmembrane Conductance Regulator
• CFTR gene
• Heterozygote