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Metagenomic analysis of viral nucleic acid extraction methods in respiratory clinical samples

25 Oct 2018

Abstract excerpt

BACKGROUND: Numerous protocols for viral enrichment and genome amplification have been created. However, the direct identification of viral genomes from clinical specimens using next-generation sequencing (NGS) still has its challenges. As a selected viral nucleic acid extraction method may determine the sensitivity and reliability of NGS, it is still valuable to evaluate the extraction efficiency of different...

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PMID: 30359242
DOI: 10.1186/s12864-018-5152-5

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