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Article

miR-874 regulates multiple-drug resistance in gastric cancer by targeting ATG16L1

11 Oct 2018

Abstract excerpt

Chemotherapy is an important treatment option for gastric cancer (GC); however, chemotherapy usually fails due to drug resistance, particularly multidrug resistance (MDR). In our previous studies, microRNA (miR)‑874 was demonstrated to serve an important role in tumour growth, apoptosis and angiogenesis. In the present study, the precise roles and underlying mechanisms of miR‑874 in MDR were investigated in GC....

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Identifiers

PMID: 30320370
DOI: 10.3892/ijo.2018.4593

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