Phenotypic and genotypic profiling of antimicrobial resistance genes and virulence factors in Pseudomonas aeruginosa isolates from keratitis patients.

doi:10.1016/j.jtos.2025.10.011

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Article

Phenotypic and genotypic profiling of antimicrobial resistance genes and virulence factors in Pseudomonas aeruginosa isolates from keratitis patients.

The ocular surface - 1 Oct 2025

Tigabu Abiye, Willcox Mark D P, Stapleton Fiona

Abstract excerpt

BACKGROUND: Pseudomonas aeruginosa (P. aeruginosa) is a major cause of ocular infections, exhibiting resistance to many antimicrobial agents and the ability to acquire further resistance through mutations and horizontal gene transfer. It employs a range of virulence factors to invade ocular tissues, leading to complications such as corneal scarring and perforation. Alarmingly, multidrug-resistant P. aeruginosa...

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PMID: 41176227
DOI: 10.1016/j.jtos.2025.10.011

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