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Article

Anti‐tumour effect of lapatinib in canine transitional cell carcinoma cell lines

23 Sept 2018

Abstract excerpt

Transitional cell carcinoma (TCC) accounts for >90% of canine malignant tumours occurring in urinary bladder, and the prognosis is poor. Our previous study, using RNA sequencing, showed that human epidermal growth factor 2 (HER2) was the most activated upstream regulator related to carcinogenesis in canine TCC. The aim of this study was to examine the anti‐tumour effect of lapatinib, a tyrosine kinase inhibitor...

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PMID: 30246405
DOI: 10.1111/vco.12434

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