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Chromatin swelling drives neutrophil extracellular trap release

10 Sept 2018

Abstract excerpt

Neutrophilic granulocytes are able to release their own DNA as neutrophil extracellular traps (NETs) to capture and eliminate pathogens. DNA expulsion (NETosis) has also been documented for other cells and organisms, thus highlighting the evolutionary conservation of this process. Moreover, dysregulated NETosis has been implicated in many diseases, including cancer and inflammatory disorders. During NETosis,...

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PMID: 30218080
DOI: 10.1038/s41467-018-06263-5

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