Article
BRCA1/2 mutations, including large genomic rearrangements, among unselected ovarian cancer patients in Korea.
Journal of gynecologic oncology - 1 Nov 2018
Kim Do Hoon, Cho Chi Heum, Kwon Sun Young, Ryoo Nam Hee, Jeon Dong Seok, Lee Wonmok, Ha Jung Sook
Abstract excerpt
OBJECTIVE: We performed small-scale mutation and large genomic rearrangement (LGR) analysis of BRCA1/2 in ovarian cancer patients to determine the prevalence and the characteristics of the mutations. METHODS: All ovarian cancer patients who visited a single institution between September 2015 and April 2017 were included. Sanger sequencing, multiplex ligation-dependent probe amplification (MLPA), and long-range...
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