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Article

Association between the T6459C point mutation of the mitochondrial MT-CO1 gene and susceptibility to sepsis among Chinese Han people.

Journal of cellular and molecular medicine - 1 Nov 2018

Shen Xiaodong, Han Guoxin, Li Shuoshuo, Song Yang, Shen Hong, Zhai Yongzhi, Wang Yingchan, Zhang Fei, Dong Ning, Li Tanshi, Yao Yongming, Zhu Haiyan

Abstract excerpt

To search for an association between sepsis and mitochondrial genetic basis, we began our study. In this study, a proband harbouring mitochondrial T6459C mutation with sepsis and his Chinese Han pedigree including 7 members of 3 generations were enrolled. General information, blood parameters and mitochondrial full sequence scanning of all members were performed, and cellular functions, including cellular...

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Identifiers

PMID: 30207067
DOI: 10.1111/jcmm.13746
PMCID: PMC6201344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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