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Candidate protein markers for radiation biodosimetry in the hematopoietically humanized mouse model

4 Sept 2018

Abstract excerpt

Abstract After a radiological incident, there is an urgent need for fast and reliable bioassays to identify radiation-exposed individuals within the first week post exposure. This study aimed to identify candidate radiation-responsive protein biomarkers in human lymphocytes in vivo using humanized NOD scid gamma (Hu-NSG) mouse model. Three days after X-irradiation (0–2 Gy, 88 cGy/min), human CD45+ lymphocytes...

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PMID: 30202043
DOI: 10.1038/s41598-018-31740-8

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