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Article

Comprehensive genetic diagnosis of acute myeloid leukemia by next-generation sequencing.

Haematologica - 1 Feb 2019

Mack Elisabeth K M, Marquardt André, Langer Danny, Ross Petra, Ultsch Alfred, Kiehl Michael G, Mack Hildegard I D, Haferlach Torsten, Neubauer Andreas, Brendel Cornelia

Abstract excerpt

Differential induction therapy of all subtypes of acute myeloid leukemia other than acute promyelocytic leukemia is impeded by the long time required to complete complex and diverse cytogenetic and molecular genetic analyses for risk stratification or targeted treatment decisions. Here, we describe a reliable, rapid and sensitive diagnostic approach that combines karyotyping and mutational screening in a single,...

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Identifiers

PMID: 30190345
DOI: 10.3324/haematol.2018.194258
PMCID: PMC6355503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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