Article
Genomic tools in acute myeloid leukemia: From the bench to the bedside.
Cancer - 15 Apr 2014
White Brian S, DiPersio John F
Abstract excerpt
Since its use in the initial characterization of an acute myeloid leukemia (AML) genome, next-generation sequencing (NGS) has continued to molecularly refine the disease. Here, the authors review the spectrum of NGS applications that have subsequently delineated the prognostic significance and biologic consequences of these mutations. Furthermore, the role of this technology in providing a high-resolution glimpse...
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