Article
Discordance of the PAM50 Intrinsic Subtypes Compared with Immunohistochemistry-Based Surrogate in Breast Cancer Patients: Potential Implication of Genomic Alterations of Discordance.
Cancer research and treatment - 1 Apr 2019
Kim Hee Kyung, Park Kyung Hee, Kim Youjin, Park Song Ee, Lee Han Sang, Lim Sung Won, Cho Jang Ho, Kim Ji-Yeon, Lee Jeong Eon, Ahn Jin Seok, Im Young-Hyuck, Yu Jong Han, Park Yeon Hee
Abstract excerpt
PURPOSE: We aimed to analyze the discordance between immunohistochemistry (IHC)-based surrogate subtyping and PAM50 intrinsic subtypes and to assess overall survival (OS) according to discordance. MATERIALS AND METHODS: A total of 607 patients were analyzed. Hormone receptor (HR) expression was evaluated by IHC, and human epidermal growth factor receptor 2 (HER2) expression was analyzed by IHC and/or fluorescence...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.