Article
Haptoglobin phenotype is a critical factor in the use of fucosylated haptoglobin for pancreatic cancer diagnosis.
Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2018
Morishita Koichi, Ito Nami, Koda Sayaka, Maeda Megumi, Nakayama Kotarosumitomo, Yoshida Kiyoshi, Takamatsu Shinji, Yamada Makoto, Eguchi Hidetoshi, Kamada Yoshihiro, Miyoshi Eiji
Abstract excerpt
Fucosylation is one of the most important glycosylations involved in cancer and inflammation. Many studies have reported significant increases in serum fucosylated haptoglobin (Fuc-Hpt) in a variety of cancer patients. In this study, we measured Fuc-Hpt using a lectin-antibody enzyme-linked immunosorbent assay (ELISA) or a novel ELISA system that used a glycan antibody for Fuc-Hpt. Hpt is known to be divided into...
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