Article
EPHA2 sequence variants are associated with susceptibility to Kaposi's sarcoma-associated herpesvirus infection and Kaposi's sarcoma prevalence in HIV-infected patients.
Cancer epidemiology - 1 Oct 2018
Blumenthal Melissa J, Schutz Charlotte, Meintjes Graeme, Mohamed Zainab, Mendelson Marc, Ambler Jon M, Whitby Denise, Mackelprang Romel D, Carse Sinead, Katz Arieh A, Schäfer Georgia
Abstract excerpt
BACKGROUND: To determine if variations exist in the KSHV host receptor EPHA2's coding region that affect KSHV infectivity and/or KS prevalence among South African HIV-infected patients. METHODS: A retrospective candidate gene association study was performed on 150 patients which were randomly selected from a total of 756 HIV-infected patients and grouped according to their KS status and KSHV serodiagnosis; namely...
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